Autism history
• 1943 – Dr. Leo Kanner at Johns Hopkins first described autism in children as “autistic disturbances of affective contact.”
• 1944 – Dr. Hans Asperger in Vienna described a similar condition later known as Asperger’s syndrome.
• 1980 – Autism was officially recognized as a distinct diagnosis in the DSM-III.
Acetaminophen (Tylenol) history and warnings
• 1878 – Chemist Harmon Northrop Morse first synthesized acetaminophen.
• 1893 – It was first used clinically in Germany to treat pain and fever.
• 1947–1948 – First used in the U.S. in a prescription drug called Triagesic (acetaminophen, aspirin, and caffeine). It was pulled from the market in 1948 after liver damage cases, likely from contamination.
• 1955 – McNeil Laboratories introduced Tylenol Elixir for Children, the first standalone acetaminophen product sold over the counter in the U.S.
• 1970s – Studies and FDA reports documented severe liver toxicity from overdose.
• 1977 – An FDA panel recommended adding the warning: “Do not exceed recommended dosage because severe liver damage may occur.”
• 1970–1977 – Reports in BMJ, JAMA, and Annals of Internal Medicine showed massive liver damage even at doses not far above recommended amounts.
Typical individual use
The average adult Tylenol user typically takes about 1,000–2,000 mg per day (about 2–4 extra-strength pills) for pain or fever, often over several days or weeks per year. However, some chronic users, those with ongoing pain, may take amounts close to the 3,000–4,000 mg daily limit regularly, which increases the risk of liver injury.
Summary
Autism was first described in 1943 in the U.S. and 1944 in Germany. Acetaminophen was first used in 1893, appeared in the U.S. in 1947–48, and became widely sold as Tylenol in 1955. Warnings about liver toxicity began in the 1970s.
WHO CREATED IT:
Harmon Northrop Morse (1848–1920) was an American chemist best known for first synthesizing acetaminophen (paracetamol) in 1878. He was a professor of chemistry at Johns Hopkins University, where he focused on organic chemistry and chemical synthesis.
Morse created acetaminophen by reducing p-nitrophenol with tin in glacial acetic acid, a process that was a significant achievement in 19th-century organic chemistry.
TIMELINE:
• 1878 – American chemist Harmon Northrop Morse first creates acetaminophen.
• 1893 – German physician Joseph von Mering is the first to use it in patients.
• 1947–48 – McNeil Laboratories in the U.S. reintroduces it in the prescription drug Triagesic.
• 1955 – McNeil launches Tylenol Elixir for Children, the first standalone acetaminophen product in the U.S.
• 1959 – Johnson & Johnson acquires McNeil Laboratories, gaining full control of Tylenol. From this point on, Tylenol became one of J&J’s biggest consumer drug brands.
AUTISM AND BIRTH DEFECTS TIMELINE
Rise in autism, learning disabilities, and birth defects
• Before 1980 – Autism was rarely diagnosed and often mislabeled as childhood schizophrenia. Birth defect rates were lower overall, and many were not tracked in detail.
• 1980 – Autism became an official diagnosis in the DSM-III, leading to increased recognition.
• Late 1980s–1990s – There was a sharp increase in autism and learning disability diagnoses, jumping from about 1 in 2,000 children in the early 1980s to about 1 in 150 by 2000. Around this time, reported birth defects also began rising, especially neurodevelopmental, heart, and reproductive abnormalities.
• 2000s–2020s – The upward trend continued. The CDC reported autism at 1 in 36 children by 2020–2023. Learning disabilities and developmental delays followed a similar growth pattern, and congenital birth defect rates also increased globally, with many linked to environmental exposures and prenatal chemical use.
Disclaimer: The information provided here is for educational and informational purposes only and is not medical advice. It should not be used to diagnose, treat, or make decisions about any medical condition. Always consult a qualified healthcare professional before making decisions about medications, pregnancy, or treatment options.
Zenia is a multifaceted artist, musician, singer, actress, and tech advisor, dedicated to inspiring transformation through authentic expression. A natural wellness advocate and activist, she supports movements, foundations, and individuals committed to meaningful change. Zenia empowers people to live from the heart, harnessing the power of music, art, lifestyle shifts, and conscious awareness. Rooted in a family legacy of yoga, meditation, holistic health, education, and law, she carries forward a tradition of healing and knowledge, blending artistry with advocacy to make a lasting impact on the world.
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